Painkiller Ghosts


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And GlaxoSmithKline ran a programme in which employees approached doctors to help them write up their experiences with the depression medicine Paxil paroxetine.

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Experimental painkiller molecule as powerful as morphine, but not addictive

Three published case studies resulted, none acknowledging the assistant writer, says company spokesman Kevin Colgin. These high-profile cases involve papers published largely in the late s or early s, and Merck, Wyeth and GlaxoSmithKline have all since changed their policies to strengthen rules on disclosure.

Yet medical-journal editors say the issue continues. These include, for example, favourable reviews for new drugs apparently penned by authors who had not previously published on that topic. Whether such ghostwriting has an adverse effect is hard to pin down. The aim of sponsoring and writing papers is simply to "broaden knowledge about the latest science", says Wyeth spokesman Doug Petkus.

But Drummond Rennie, deputy editor at JAMA , says that ghostwritten papers tend to have more positive conclusions and can be used to market off-label uses of drugs. It discovered that a third of the county knew someone who had overdosed on the medicine. Addiction is treatable, and the solution requires a healthy blend of compassion, understanding and vigilance. As with every addiction, we need to break down the stigma and make sure that people can share the fact that they have a problem.

A replacement for prescription opioids

Health professionals need to do their bit too. Pharmacists have to challenge regulars who regularly pick up packs of codeine, and doctors must keep a watchful eye on how long a patient is prescribed pain relief, regularly reviewing their needs. We may not know the extent of the problem of prescribed painkiller addiction, but we know the solution. And it starts by talking about drugs again.

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America's lethal plague of prescription painkiller addiction may now be spreading to Britain

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America's lethal plague of prescription painkiller addiction may now be spreading to Britain

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